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. 2017 Mar 3;6(4):e1295903. doi: 10.1080/2162402X.2017.1295903

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Figure 3. — Glioblastoma (GBM) tumor tissue does not show strong upregulation of CTLA4, PDCD1 and IDO1. Analysis of differential expression of CTLA4 (A, D), PDCD1 (B, E) and IDO1 (C, F) between normal brain tissue sample (for REMBRANDT, n = 21; for TCGA, n = 11) and GBM tissue sample (for REMBRANDT, n = 214; for TCGA, n = 202) (mean ± s.d., Mann–Whitney test; p-value as indicated). Of note, TCGA and REMBRANDT data sets were analyzed by different expression-analysis platforms and standardized by different post-processing and normalization analyses and hence their overall gene-expression counts have different (but proportional) scales.