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. 2016 Jan 1;37(4):1251–1263. doi: 10.1177/0271678X16653615

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Mean left/right regional V_T and DVR (mean ± SD) time course data before (D0-1) and after (D0 + 6, D0 + 35) pilocarpine-induced SE in selected brain structures (* highlights p values < 0.05 and ** for p < 0.009 computed with t test against baseline): (a) Logan plot model, (b) one tissue compartment model, (c) Logan reference model, (d) simplified reference tissue model. Changes were considered significant in a structure when they were significant both on the left and the right side of the given structure. Seven rats had arterial input functions and could be analysed with the 1TC and LR models; all nine could be used for the LR and SRTM models.