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. 2016 Jan 1;37(4):1251–1263. doi: 10.1177/0271678X16653615

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Mean left/right regional VT and SUV (mean ± std) time course data before (D0-1) and after (D0 + 6, D0 + 35) pilocarpine-induced SE in selected brain structures (* highlights p values < 0.05 and ** for p < 0.005, *** for p < 5*10 ^− 4, + for p < 5*10⁻⁵, ++ for p < 5*10⁻⁶ computed with t test against baseline): (a) SUV, (b) 1TC – one tissue compartment model using a normalised mean arterial input function (normalised according to the injected dose and the weight of each rat, and averaged over seven rats). Changes were considered significant in a structure when they were significant both on the left and the right side of the given structure.