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. 2017 May 3;12(5):e0176609. doi: 10.1371/journal.pone.0176609

Fig 4. Acute effects of STD or HIT resistance exercise on p38 MAPK phosphorylation (p-p38) and H3K4 trimethylation (H3K4me3) in vivo.

Fig 4

A Representative western Blots of human muscle homogenates at baseline (pre) and up to 24 h post RE. B Quantification of the average area of the H3K4me3 staining signal in human skeletal muscle nuclei pre and 4 h post STD and HIT demonstrating significantly lower nuclear H3K4me3 staining intensity following HIT compared to STD. C Representative pictures of human skeletal muscle cross-sections stained for H3K4me3 (red, Alexa 555), dystrophin as sarcolemma marker (green, Alexa 488) and DAPI (blue) before (pre) and after (4 h post) RE. Data presented as mean ± SD. * indicates statistical significance, i.e. p < 0.05.