Table 2.
Positivity rate, sensitivity, specificity, positive predictive value, negative predictive value, detection rate for men and women at different cutoffs
| Men |
Women |
|||
|---|---|---|---|---|
| % | (95% CI) | % | (95% CI) | |
| FIT 10 | ||||
| PR | 10.8 | (8.6–13.5) | 8.4 | (6.5–10.9) |
| Sensitivity | 39.7 | (28.8–51.7) | 35.3 | (23.5–49.2) |
| Specificity | 92.6 | (90.2–94.5) | 94.0 | (91.7–95.7) |
| PPV | 39.1 | (28.4–51.0) | 34.6 | (23.0–48.8) |
| NPV | 92.7 | (90.4–94.7) | 94.2 | (91.9–95.8) |
| DR | 4.2 | (2.9–6.1) | 2.9 | (1.8–4.6) |
| FIT 20 | ||||
| PR | 6.3 | (4.6–8.4) | 5.0 | (3.5–7.0) |
| Sensitivity | 29.4 | (19.8–41.2) | 33.3 | (21.8–47.2) |
| Specificity | 96.4 | (94.6–97.7) | 97.5 | (95.9–98.5) |
| PPV | 50.0 | (35.0–65.0) | 54.8 | (37.4–71.1) |
| NPV | 92.0 | (89.5–93.9) | 94.2 | (92.0–95.8) |
| DR | 3.1 | (2.0–4.8) | 2.8 | (1.7–4.4) |
| FIT 30 | ||||
| PR | 5.0 | (3.6–7.0) | 3.6 | (2.4–5.3) |
| Sensitivity | 29.4 | (19.8–41.2) | 25.5 | (15.4–39.1) |
| Specificity | 98.0 | (96.3–98.8) | 98.4 | (97.0–99.2) |
| PPV | 62.5 | (44.9–77.3) | 59.0 | (38.2–77.2) |
| NPV | 92.1 | (89.6–94.0) | 93.6 | (91.4–95.3) |
| DR | 3.1 | (2.9–4.8) | 2.1 | (1.2–3.6) |
| FIT 40 | ||||
| PR | 3.8 | (2.5–5.6) | 3.2 | (2.1–5.0) |
| Sensitivity | 25.0 | (16.1–36.6) | 21.6 | (12.4–34.9) |
| Specificity | 98.8 | (97.4–99.4) | 98.4 | (97.0–99.2) |
| PPV | 70.8 | (50.2–85.4) | 55.0 | (33.6–74.7) |
| NPV | 91.7 | (89.2–93.6) | 93.3 | (91.0–95.1) |
| DR | 2.7 | (1.7–4.2) | 1.8 | (1.0–3.2) |
FIT: fecal immunochemical test; FIT 10: cutoff level 10 µg/g feces; FIT 20: cutoff level 20 µg/g feces; FIT 30: cutoff level 30 µg/g feces; FIT 40: cutoff level 40 µg/g feces; PR: positivity rate; PPV: positive predictive value; NPV: negative predictive value; DR: detection rate; CI: confidence interval.