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Effect of ER ligands on cell proliferation in BELZ cell lines. Cell proliferation was analyzed in BELZ (A), BELZ ERβ-1 (B), and BELZ ERβ-2 (C) cells following exposure during 7 days to increasing concentrations of E2 (■), PPT (○), and 8β-VE2 (▴). Data were normalized with respect to the proliferation of control cells set at 1. Each normalized data point represents the mean of 3 independent experiments ± SD.
