Regulation of endogenous ER-target genes in BELZ cell lines. The levels of PR, fibulin-1, retinoic acid receptor-α (RARα), cyclin D1, and RIP140 mRNA levels were measured by RT-qPCR in the BELZ and BELZ ERβ-2 cell lines, after 1 day of treatment with ethanol (Control) or estrogen (E2 10 nM). Results are expressed as fold vs level in BELZ cells in the absence of ligand (A) or as fold E2 induction (B).