Table 2.
Seven Weeks | Four Months | |||
---|---|---|---|---|
Control | POMCΔDCR | Control | POMCΔDCR | |
Insulin, ng/mL | 1.12 ± 0.18 | 2.68 ± 0.63a | 0.94 ± 0.21 | 1.99 ± 0.42a |
HOMA-IR | 11.98 ± 1.99 | 35.73 ± 9.78a | 8.64 ± 2.31 | 23.22 ± 9.78a |
Leptin, ng/mL | 1.42 ± 0.21 | 6.60 ± 1.86a | 2.34 ± 0.94 | 12.12 ± 2.87b |
GLP-1, pg/mL | 84.95 ± 0.75 | 93.06 ± 1.43b | 84.62 ± 0.99 | 81.99 ± 1.66 |
P < .05 compared with control mice at the same age.
P < .01 compared with control mice at the same age.