Table 2.
Opioid medication use during post-surgical study period (expressed in IV equivalent of morphine in mg).
| IVA (n = 406) | Non-IVA (n = 203) | p value | |
|---|---|---|---|
| Opioids | |||
| Total, mean, mg (SD) | 209.61 (552.09) | 163.89 (232.44) | 0.15 |
| Fentanyl injection, n (%) | 365 (90) | 179 (88.2) | 0.58 |
| Fentanyl injection, mean, mg (SD) | 99.9 (543.47) | 77.4 (193.18) | 0.50 |
| Hydromorphone injection, n (%) | 147 (36.2) | 57 (28.1) | 0.05 |
| Hydromorphone injection, mean, mg (SD) | 59.0 (90.54) | 107.3 (148.01) | 0.91 |
| Hydromorphone oral, n | 6 (1.5) | 7 (3.4) | 0.14 |
| Hydromorphone oral, mean, mg (SD) | 44.43 (90.54) | 22.85 (148.01) | 0.02 |
| Meperidine injection, n (%) | 4 (0.1) | 4 (2.0) | 0.45 |
| Meperidine injection, mean, mg (SD) | 4.16 (4.16) | 3.33 (3.33) | 0.31 |
| Methadone oral, n | 2 (0.49) | 0 | 0.55 |
| Methadone oral, mean, mg (SD) | 388 (0) | 0 | N/A |
| Morphine injection, n (%) | 147 (36.2) | 78 (38.4) | 0.0017 |
| Morphine injection, mean, mg (SD) | 69.3 (249.97) | 42.8 (69.48) | 0.53 |
| Morphine oral, n | 1 (0.2) | 2 (1.0) | 0.26 |
| Morphine oral, mean, mg (SD) | 176.82 (0) | 59.94 (56.51) | 0.06 |
| Oxycodone oral, n | 388 (95.6) | 186 (91.6) | 0.06 |
| Oxycodone oral, mean, mg (SD) | 73.54 (71.56) | 51.93 (38.66) | 0.002 |
SD: standard deviation; IVA: intravenous acetaminophen; IV: intravenous.