Table 3.
Hazards ratios (HR) of breast cancer and corresponding 95% confidence intervals (CI) according to tertiles of dietary inflammatory index (DII) within BMI subgroups, in the Iowa Women’s Health Study, 1986-2011.
Cases | DII Tertiles, HR (95% CI)b | p trendc |
Pinteraction (DIIcontinous ) |
P interaction (DII tertiles) |
DII continuousd | |||
---|---|---|---|---|---|---|---|---|
< −2.08 | −2.09 to −0.05 | > −0.05 | 0.02 | 0.06 | ||||
BMI (kg/m2) | ||||||||
<25 | 1031 | 1 a | 1.08 (0.93, 1.26) | 1.06 (0.89, 1.25) | 0.56 | 0.99 (0.96, 1.03) | ||
25-30 | 1160 | 1 a | 0.98 (0.85, 1.14) | 1.04 (0.89, 1.22) | 0.55 | 1.01 (0.98, 1.05) | ||
>30 | 743 | 1 a | 1.22 (1.01, 1.48) | 1.35 (1.10, 1.66) | 0.01 | 1.05 (1.01, 1.10) |
Reference category.
adjusted for age, smoking status, pack-years of smoking, education, HRT use, oral contraceptive use, number of live births, education, age at menarche, age at menopause and history of hysterectomy and total energy intake.
P-value for trend determined through linear method.
Each point corresponding to a 1-unit increment in DII (corresponding to a 0.5 standard deviation increase)..