Table 2. Adjusted mean differences between groups in change from baseline at 3 months.

Outcome	HI Group Mean (SEM)	LI Group Mean (SEM)	Point Estimate (95% CI)	p-value
Stair Climbing Test (s)	-3.89 (0.35)	-3.28 (0.36)	-0.61 (-1.56, 0.35)	0.21
Timed-Up-and-Go Test (s)	-1.35 (0.14)	-1.01 (0.14)	-0.34 (-0.71, 0.04)	0.08
6-minute Walk Test (m)	38.83 (7.18)	23.39 (7.48)	15.45 (-4.51, 35.40)	0.13
WOMAC	-19.60 (1.02)	-19.48 (1.05)	-0.12 (-2.94, 2.70)	0.93
SF-12 Physical Component Scale	9.82 (0.93)	6.80 (0.99)	3.02 (0.39, 5.65)	0.02
SF-12 Mental Component Scale	2.56 (0.76)	3.57 (0.80)	-1.00 (-3.14, 1.14)	0.36
Knee Extension (°)	-0.61 (0.30)	-0.35 (0.31)	-0.26 (-1.09, 0.56)	0.53
Knee Flexion (°)	-1.93 (0.93)	-2.10 (0.96)	0.17 (-2.40, 2.73)	0.90
Quadriceps Strength (Nm/kg)	0.02 (0.04)	-0.05 (0.04)	0.08 (-0.03, 0.18)	0.14
Hamstrings Strength (Nm/kg)	0.03 (0.02)	-0.00 (0.02)	0.03 (-0.03, 0.09)	0.28
Quadriceps Activation (%)	11.70 (1.53)	8.52 (1.60)	3.18 (-1.07, 7.43)	0.14

Reported means are change from baseline adjusting for baseline, sex, and clinical site. Negative values of knee extension represent hyperextension. HI=High-intensity group. LI= Low-intensity group. WOMAC=Western Ontario and McMaster Universities Osteoarthritis Index. SF-12=Short-form 12.