Table 5.
Multivariable logistic regression analyses of CT features combined with clinical variables predicting the presence of EGFR mutation in lung adenocarcinoma
| Variable | P | Odds ratio | 95% CI |
|---|---|---|---|
| Gender | |||
| Female | — | Reference | NA |
| Male | 0.648 | 1.207 | 0.538, 2.710 |
| Smoking | |||
| Yes | — | Reference | NA |
| No | 0.004 | 4.039 | 1.572, 10.377 |
| Histologic subtype | |||
| Lepidic | 0.266 | 2.279 | 0.533, 9.744 |
| Acinar | 0.012 | 5.110 | 1.430, 18.256 |
| Papillary | 0.026 | 5.227 | 1.223, 22.333 |
| Solid | — | Reference | NA |
| CEA | |||
| ≤2.6 | 0.318 | 1.434 | 0.706, 2.913 |
| >2.6 | — | Reference | NA |
| GGO proportion | |||
| GGO negative | — | Reference | NA |
| Any GGO | 0.023 | 2.731 | 1.147, 6.503 |
CI, confidence interval; CEA, carcinoembryonic antigen; CT, computed tomography; EGFR, epidermal growth factor receptor; GGO, ground‐glass opacity; NA, not applicable.