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. 2017 May 4;11:78. doi: 10.3389/fnbeh.2017.00078

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Copyright © 2017 Vore, Doremus-Fitzwater, Gano and Deak.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokine expression in male and female rats from experiment 4. This figure shows mRNA expression changes in male and female rats following i.p. LPS injection in IL-6 (A,B), IL-1 (C,D), TNF-α (E,F) and IκBα (G,H). Samples were collected at 0, 45, 90, 180 and 360 min following LPS injection. Data is expressed relative to ultimate control (Vehicle animals at the baseline time point) normalized to β-Actin. A significant main effect of time point is denoted by a lettering system in which time points that differ in letter are significantly different. A pound sign indicates a significant interaction between adolescent exposure and challenge stimulus at a given time point. All post hoc comparisons were made using Fisher’s Least Significant Difference post hoc test (p < 0.05).