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A plaque burden in the brain of mice. (a-b) IHC-positive Aβ plaques in neocortex of 9-month-old mice. (c) Comparison of IHC-positive Aβ plaque density in neocortex of 9-month-old mice. (d-e) Congo red-positive Aβ plaques in neocortex of 9-month-old mice. (f) Comparison of Congo red-positive Aβ plaque density in neocortex of 9-month-old animals. Denote p < 0.05 versus control group.
