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. 2017 May 4;18:20. doi: 10.1186/s40360-017-0129-6

Table 1.

Concentration and type of assay used for each experiment

Concentrations used Quantification method
A B Drug μg/ml μM
1 PZQ SQV PZQ 20 64 HPLC
SQV 20 29.8
2 SQV PZQ [3H] SQV 1.07 Radiolabeled assay
PZQ 20 64
3 IVM SQV [3H] IVM 0.01 Radiolabeled assay
SQV 20 29.8
4 SQV IVM SQV 20 29.8 HPLC
IVM 20 22.75
5 PZQ EFV PZQ 20 64 HPLC
EFV 20 63.4
6 PZQ NVP PZQ 20 64 HPLC
NVP 20 75.1
7 IVM NVP [3H] IVM 0.01 Radiolabeled assay
NVP 20 75.1
8 NVP IVM [3H] NVP 1.5 Radiolabeled assay
IVM 20 22.75
9 IVM LPV [3H] IVM 0.02 Radiolabeled assay
LPV 20 31.81
10 LPV IVM [3H] LPV 1.5 Radiolabeled assay
IVM 20 22.75
11 IVM EFV [3H] IVM 0.01 Radiolabeled assay
EFV 20 63.34
12 EFV IVM [14C] EFV 0.01 Radiolabeled assay
IVM 20 22.75

Drug A Drug whose transport is under investigation

Drug B Interacting drug