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(A) Intracellular uptake of PTX of free PTX, PTX+TET, P+T/LPN, and P+T/iRGD LPN in A2780 and A2780/PTX cells after 1 h, 2 h, and 4 h incubation. (Various groups vs free P+T #p < 0.05, P+T/LPN vs P+T/iRGD LPN ‡p < 0.05). (B) Rhodamine 123 accumulation of free Rho 123, Rho 123+TET, R+T/LPN, and R + T/iRGD LPN in A2780/PTX cells for 4 h pretreatment and 1 h efflux. Scale bar is 50 μm.
