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. 2017 Apr 20;2017:5198798. doi: 10.1155/2017/5198798

Figure 1.

Figure 1

JX-594 was generated as insertion of human GM-CSF and β-galactosidase at in between early/late promoter of TK gene. GM-CSF is an immune-stimulatory cytokine, which induces immune response against tumor cells.