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. 2017 Apr 7;114(14):244–249. doi: 10.3238/arztebl.2017.0244

Table. Initial anticoagulation and maintenance treatment for DVT-UE*1.

Substance*2 Initial dose Maintenance dose
LMWH
Certoparin 8000 IU (2/day s. c.) 8000 IU (2/day s. c.)
Dalteparin 100 IU/kg BW (2/day s. c.) 200 IU/kg BW (1/day s. c.) 100 IU/kg BW (2/day s. c.) 200 IU/kg BW (1/day s. c.)
Enoxaparin 1.0 mg/kg BW (2/day s. c.) 1.0 mg/kg BW (2/day s. c.)
Tinzaparin 175 IU/kg BW (1/day s. c.) 175 IU/kg BW (1/day s. c.)
UFH
Heparin sodium/calcium Bolus: 5000 IU 15–20 IU/kg BW/h (i. v.) ca. 15–20 IU/kg BW/h (i. v. _under aPTT monitoring)
Pentasaccharide
Fondaparinux 7.5 mg (1/day s. c.) <50 kg: 5 mg (1/day s. c.) >100 kg: 10 mg (1/day s. c.) 7.5 mg (1/day s. c.) <50 kg: 5 mg (1/day s. c.) >100 kg: 10 mg (1/day s. c.)
DOAC
Dabigatran – 150 mg (2/day p. o.)
Rivaroxaban 15 mg (2/day. 3 weeks p. o.) 20 mg (1/day p. o.)
Apixaban 10 mg (2/day. 1 week p. o.) 5 mg (2/day p. o.)
Edoxaban – 60 mg (1/day p. o.)