Table 5.
Most reported risk factors among the 27 cases exposed to hydroxyzine <100 mg
| Risk factors of acquired long QT syndrome | Cases, n (%) |
|---|---|
| Cardiovascular disorders + concomitant drugs known to induce QT prolongation/TdP | 13 (48.5) |
| Concomitant Drugs known to induce QT prolongation/TdP | 5 (18.5) |
| Cardiovascular disorders | 2 (7.5) |
| Metabolic abnormalities + concomitant drugs known to induce QT prolongation/TdP | 2 (7.5) |
| Genetic disorders | 2 (7.5) |
| Metabolic abnormalities | 1 (3.5) |
| Renal disease | 1 (3.5) |
| Renal disease + concomitant drugs known to induce QT prolongation/TdP | 1 (3.5) |
| Total | 27 (100) |
n, refers to the number of cases; TdP, torsade de pointes; QT, QT interval is defined as the time between the beginning of the Q wave and the end of the T wave of the PQRST cardiac activity cycle.