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. 2017 Mar 14;7:81–89. doi: 10.1016/j.omtn.2017.02.009

Figure 6.

Figure 6

Phenotype Rescue following tcDNA Treatment in SMA Mice

(A) Phenotypic rescue in type III SMA mice at 12 weeks of age after tcDNA treatment, compared to SMA control. (B) Toes and tails necrosis rescue in treated mice (right picture) compared to SMA control (left picture). (C) Ears rescue in treated mice (right picture) compared to SMA control (left picture). (D) Tails length of mice according to weeks. The darker gray curve corresponds to the size of the tails of type III SMA mice treated with TcI7 during 12 weeks (n = 4), the black curve is the size of the tails of type III SMA untreated mice (n = 11) and the lighter gray one corresponds to the tails length of type III SMA mice treated with TcI7 during 4 weeks only (n = 3).