Table 1.
Respiratory Function Evaluation in WT FVB Mice and SMA Type III Mice
| Ti (ms) | Te (ms) | PIF (mL/s) | PEF (mL/s) | TV (mL) | EV (mL) | RT (ms) | MV (mL) | f (bpm) | EIP (ms) | EEP (ms) | Penh | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FVB | ||||||||||||
| Mean | 129.6 | 180.8 | 2.9 | 1.9 | 0.2 | 0.2 | 109.5 | 44.4 | 205.5 | 1.2 | 19.9 | 0.444 |
| SEM | 7.18 | 50.45 | 0.30 | 0.33 | 0.03 | 0.03 | 37.71 | 8.68 | 20.47 | 0.17 | 4.37 | 0.061 |
| SMA | ||||||||||||
| Mean | 130.1 | 242.8 | 2.4 | 1.3 | 0.2 | 0.2 | 157.5 | 33.3 | 179.0 | 1.2 | 23.4 | 0.353 |
| SEM | 8.81 | 29.20 | 0.35 | 0.23 | 0.01 | 0.01 | 22.48 | 5.23 | 15.41 | 0.08 | 2.40 | 0.026 |
| p Value | ||||||||||||
| 0.5130 | 0.0472 | 0.4490 | 0.0747 | 0.1816 | 0.2039 | 0.0423 | 0.1400 | 0.1136 | 0.8545 | 0.1899 | 0.0097 | |
| = | + | = | = | = | = | + | − | − | = | + | − | |
Te, expiratory time; EEP, end-expiratory pause; EIP, end-inspiratory pause; PIF, peak inspiratory flow; PEF, peak expiratory flow.