Table 3.
Effect of A. eupatoria extracts on thermal hyperalgesia using the plantar test on a cisplatin-induced pain models
| Treatment | Paw-withdrawal Duration (sec) | ||||
|---|---|---|---|---|---|
| 0 week | 1 week | 2 week | 3 week | 4 week | |
| Normal | 0.81± 0.2 | 0.84± 0.1 | 0.84± 0.2 | 0.80± 0.3 | 0.81± 0.2 |
| Control | 0.83± 0.3 | 10.4± 0.1 | 11.6± 0.3 | 12.3± 0.5 | 12.8± 0.3 |
| Gabapentin | 0.87± 0.3 | 4.5± 0.1 | 5.1± 0.1 | 6.1± 0.1 | 7.4± 0.1 |
| A. eupatoria extract | 0.84± 0.4 | 3.2± 0.3 | 3.5± 0.1 | 3.4± 0.1 | 3.7± 0.1 |
Values are expressed Mean ± SEM, (n=6), p<0.05 compared to the control group. One way ANOVA followed by Tukey’s Multiple Comparison Test.