Table 4.
Effect of A. eupatoria extracts on cold-allodynia hyperalgesia using the chemical test on a cisplatin-induced pain models
| Treatment | Paw-withdrawal Duration (sec) | ||||
|---|---|---|---|---|---|
| 0 week | 1 week | 2 week | 3 week | 4 week | |
| Normal | 16.2± 0.3 | 16.0± 0.1 | 15.8± 0.3 | 15.7± 0.1 | 16.3± 0.4 |
| Control | 15.3± 0.4 | 10.4± 0.3 | 7.3± 0.1 | 5.7± 0.1 | 4.9± 0.2 |
| Gabapentin | 16.0± 0.2 | 11.5± 0.2 | 10.5± 0.2 | 9.1± 0.2 | 7.5± 0.3 |
| A. eupatoria extract | 15.7± 0.3 | 11.8± 0.2 | 10.8± 0.3 | 11.2± 0.3 | 10.8± 0.2 |
Values are expressed Mean ± SEM, (n=6), p<0.05 compared to the control group. One way ANOVA followed by Tukey’s Multiple Comparison Test.