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. 2017 Mar 14;7(3):e1056. doi: 10.1038/tp.2017.10

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Copyright © 2017 The Author(s)

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Attenuation in the CARS scale correlates with CGI attenuation. CARS scores and CGI-I values for completers are shown after the end of the trial (D90). Bumetanide treated are in blue circle (N=52) and Placebo in orange triangles (N=21). Note that the much- or very-much-improved children with CGI evaluation were almost entirely restricted to the bumetanide-treated group (only one placebo) and correlated with the most important CARS attenuation (ordinate). CARS, Childhood Autism Rating Scale; CGI-I, Clinical Global Impressions Improvement scale.