Table 3. Baseline sociodemographic characteristics associated with remission by citalopram dosea.
| Characteristics |
20 mg per die; N=357 (60.4%) |
ORb | P-value |
40 mg per die; N=234 (39.6%) |
ORb | P-value | ||
|---|---|---|---|---|---|---|---|---|
| REM % | NO REM % | REM % | NO REM % | |||||
| Overall | 35.9 | 64.1 | 24.4 | 75.6 | ||||
| Ethnicity | 0.8622 | 0.0872 | ||||||
| Non-Caucasianc | 35.2 | 64.8 | 0.96 | 15.8 | 84.2 | 0.50 | ||
| Caucasian | 36.1 | 63.9 | 27.1 | 72.9 | ||||
| Sex | 0.5845 | 0.1300 | ||||||
| Female | 36.9 | 63.1 | 1.13 | 27.9 | 72.1 | 1.63 | ||
| Male | 34.1 | 65.9 | 19.1 | 80.9 | ||||
| Marital status | 0.2900 | 0.8200 | ||||||
| No more married | 45.5 | 54.5 | 1.41 | 22.9 | 77.1 | 0.83 | ||
| Never married | 33.7 | 66.3 | 0.86 | 22.2 | 77.8 | 0.80 | ||
| Married | 37.1 | 62.9 | 26.4 | 73.6 | ||||
| Employment status | 0.5970 | 0.0326 | ||||||
| Unemployed and retired | 36.4 | 63.6 | 0.88 | 16.0 | 84.0 | 0.45 | ||
| Employed | 39.5 | 60.5 | 29.8 | 70.2 | ||||
| Educationd | 0.2155 | 0.0484 | ||||||
| <College | 41.1 | 58.9 | 1.36 | 19.3 | 80.7 | 0.51 | ||
| ⩾College | 33.9 | 66.1 | 32.0 | 68.0 | ||||
| Incomee | 0.2000 | 0.1100 | ||||||
| Low | 33.3 | 66.7 | 1.02 | 17.9 | 82.1 | 0.48 | ||
| Middle | 43.0 | 57.0 | 1.54 | 19.8 | 80.2 | 0.54 | ||
| High | 32.8 | 67.2 | 31.3 | 68.8 | ||||
| Experienced traumatic event | 0.3318 | 0.5510 | ||||||
| No | 37.4 | 62.6 | 1.25 | 23.1 | 76.9 | 0.83 | ||
| Yes | 32.5 | 67.5 | 26.5 | 73.5 | ||||
| Witnessed traumatic event | 0.3520 | 0.6650 | ||||||
| No | 36.9 | 63.1 | 1.25 | 23.8 | 76.2 | 0.87 | ||
| Yes | 31.9 | 68.1 | 26.5 | 73.5 | ||||
| Drug abuse | 0.6800 | 0.1820 | ||||||
| No | 35.6 | 64.4 | 0.55 | 19.6 | 80.4 | 0.24 | ||
| Yes | 50.0 | 50.0 | 50.0 | 50.0 | ||||
| Insurance status | 0.9000 | 0.1500 | ||||||
| No insurance | 39.8 | 60.2 | 1.12 | 18.4 | 81.6 | 0.49 | ||
| Public insurance | 40.0 | 60.0 | 1.13 | 0.0 | 100.0 | 0.00 | ||
| Private insurance | 37.2 | 62.8 | 31.6 | 68.4 | ||||
| Mean (s.d.) | Mean (s.d.) | ORb | P-value | Mean (s.d.) | Mean (s.d.) | ORb | P-value | |
|---|---|---|---|---|---|---|---|---|
| Age (years; units=10)f | 39.5 (13.0) | 42.4 (13.8) | 0.85 | 0.0565 | 38.2 (13.4) | 42.1 (12.4) | 0.78 | 0.0470 |
| Years of education (units=4)f | 13.8 (3.4) | 14.5 (3.3) | 0.78 | 0.0805 | 14.6 (3.3) | 14.4 (2.9) | 1.08 | 0.7421 |
| Income ($/month; units=1000)f | 2543 (2445) | 2743 (2964) | 0.97 | 0.5208 | 3506 (4367) | 2824 (4682) | 1.03 | 0.3620 |
| Age at onset of first MDE (units=10)f | 27.0 (15.0) | 27.0 (15.2) | 1.00 | 0.9722 | 25.9 (13.0) | 24.9 (14.1) | 1.05 | 0.6320 |
| Number of MDEs (units=5)f | 3.7 (6.8) | 6.1 (8.0) | 0.76 | 0.0152 | 4.2 (7.5) | 6.6 (11.7) | 0.86 | 0.1980 |
| QIDS-SR16 (difference W4-Enroll; units=1)f | −6.7 (4.2) | −5.9 (3.7) | 0.95 | 0.0765 | −6.4 (4.2) | −6.6 (3.8) | 1.01 | 0.7392 |
Abbreviations: MDE, major depressive episode; OR, odds ratio; QIDS-SR16, Quick Inventory of Depressive Symptomatology Self-Report; REM, remission.
Remission was defined as a score ⩽5 at week 6 on the 16-item QIDS-SR16.
For characteristics for which the measurement is categorical, the comparison is with the group listed last under the category or with the opposite characteristic. For characteristics for which the measurement is continuous, the odds ratio is relative to an increase in the measurement by the number of units indicated.
Asian, American Indian or Alaskan Native, Native Hawaiian/Other Pacific Islander or multiracial.
<College=⩽16 years of schooling; ⩾College=⩾16 years of schooling.
Low=monthly gain ⩽$1000; Middle=monthly gain $1000–$2500; High=monthly gain>$2500.
Units are relevant to odds ratios only OR, MDE.