Table 2. Diagnosis effects and the sex-by-diagnosis interaction effect on fractional anisotropy values in frontal and non-frontal connectivity tracts.
Frontal tracts |
Diagnostic effect in males |
Diagnostic effect in females |
Sex-by-diagnosis interaction |
|||
---|---|---|---|---|---|---|
F | P-value | F | P-value | F | P-value | |
Anterior segment AF left | 12.75 | 0.001a | 0.09 | 0.764 | 8.80 | 0.003a |
Anterior segment AF right | 8.90 | 0.003a | 1.56 | 0.215 | 10.97 | 0.001a |
Long segment AF left | 7.21 | 0.008a | 0.18 | 0.675 | 5.32 | 0.022a |
Long segment AF right | 0.60 | 0.444 | 0.32 | 0.573 | 1.22 | 0.272 |
Cingulum left | 13.15 | <0.001a | 0.01 | 0.943 | 7.67 | 0.006a |
Cingulum right | 9.87 | 0.002a | 0.01 | 0.937 | 5.66 | 0.018a |
Uncinate left | 14.13 | <0.001a | 0.30 | 0.588 | 9.86 | 0.002a |
Uncinate right | 12.06 | 0.001a | 1.37 | 0.245 | 12.33 | 0.001a |
IFOF left | 11.80 | 0.001a | 0.09 | 0.771 | 5.89 | 0.016a |
IFOF right | 10.75 | 0.001a | 0.00 | 0.988 | 6.04 | 0.015a |
Non-frontal tracts | ||||||
Posterior segment AF left | 5.06 | 0.026a | 0.00 | 0.975 | 2.73 | 0.100 |
Posterior segment AF right | 4.30 | 0.040a | 0.11 | 0.737 | 3.14 | 0.078 |
ILF left | 8.92 | 0.003a | 0.70 | 0.408 | 3.08 | 0.081 |
ILF right | 6.02 | 0.016a | 0.01 | 0.946 | 2.82 | 0.095 |
Abbreviations: AF, arcuate fasciculus; IFOF, inferior frontal occipital fasciculus; ILF, inferior longitudinal fasciculus; IQ, intelligence quotient.
Scanning centre, age and full scale IQ, were all included as covariates.
P-values are significant at a level <0.05 after Holm-Bonferroni correction.