Spectrum of imaging appearances of dedifferentiated liposarcoma in three
different patients. (a) Axial intravenous contrast
material–enhanced CT image of dedifferentiated liposarcoma in a
58-year-old man shows areas of sharply demarcated fat (*) and
blended fat (arrowheads), as well as larger enhancing solid components
(straight arrow), with a less well-defined margin (curved arrow).
(b) Axial intravenous and oral contrast
material–enhanced CT image of dedifferentiated liposarcoma in a
72-year-old man shows progression to fewer areas of blended fat (arrowhead),
with larger myxoid (*) and solid enhancing (arrows)
components. (c) Axial intravenous and oral contrast
material–enhanced CT image of dedifferentiated liposarcoma in a
68-year-old woman shows that in addition to blended fat (arrowhead) in a larger
solid mass, coarse calcification (arrow) correlating with metaplasia or
chondro-osseous components can also be depicted. (d)
Photomicrograph of dedifferentiated liposarcoma with well-differentiated
components shows an abrupt transition between the nonlipogenic highly cellular
dedifferentiated component (*) and the well-differentiated
lipomatous component. (H-E stain; original magnification, ×40.)