Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 16;45(8):4606–4618. doi: 10.1093/nar/gkx185

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press on behalf of Nucleic Acids Research 2017.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

PMC Copyright notice

Figure 1. — Genomic features of the Csn locus during lactation. (A–C) ChIP-seq data for CTCF, STAT5, H3K27ac and H3K4me3 provided structural information on the locus (upper panel). The orientation of genes (panel A) is indicated by solid arrows. Green arrows, genes highly expressed in mammary tissue; black arrows, genes not expressed, or at very low levels, in mammary tissue; white arrow, Sult1d1, which is expressed at low levels in mammary tissue and induced upon deletion of CTCF site A. Four STAT5-based super-enhancers (red asterisks in the panel B and blue bars in panel C) and two solitary enhancers (black asterisks in the panel B) were identified. The presence of Pol II and total RNA transcripts was associated with transcriptional units and enhancers (panel C). Arrows in panel B indicate the orientations of CTCF binding sites.