Table 1. mRNA levels of mammary-specific Csn genes and non-mammary genes in the extended Csn locus during pregnancy and lactation.
| Gene | p6 (FPKM) | L1 (FPKM) | Fold change | |
|---|---|---|---|---|
| Mammary-specific genes | Csn1s1 | 1,200 | 87,950 | 74 |
| Csn2 | 3,100 | 193,500 | 63 | |
| Csn1s2a | 1,250 | 164,000 | 132 | |
| Csn1s2b | 1 | 13,600 | 10,490 | |
| Csn3 | 220 | 57,850 | 264 | |
| Non-mammary genes | Sult1b1 | 0 | 0 | n/a |
| Sult1d1 | 0.1 | 6 | 60 | |
| Sult1e1 | 0 | 0 | n/a | |
| Prr27 | 0 | 0 | n/a | |
| Odam | 0.07 | 2 | 28 | |
| Cabs1 | 0 | 0 | n/a | |
| Smr3a | 0 | 0 | n/a | |
| Smr2 | 0 | 0 | n/a |
mRNA levels of mammary-specific genes and non-mammary genes under the control of lactogenic hormones were measured by RNA-seq (4) at day 6 of pregnancy (p6) and day 1 of lactation (L1). Mammary-specific Csn genes were induced up to several thousand-fold during pregnancy, whereas genes not specific to mammary tissue, within or outside the Csn, locus were induced <60-fold. n/a, no activation.