Fig. 3. Diverse routes to hexT-pyrazole 15Y; (a) B (see Table 2), AcOH, 60 °C, overnight; (b) aq. NH3/MeNH2, room temperature, 30 min; (c) A (see Table 2), MeCN, 50 °C, overnight; (d) DDQ/CH2Cl2; (e) 10% TFA/CH2Cl2. R: p-aminocarbonylphenyl; wavy bond to hexT denotes 5′-C6-amino-linker; bold bond denotes connection to CPG solid support; filled circle denotes solid support.
