Table 1.
CYP4F2 transgenic (TG) mice exhibit both hypertension and hyperglycemia.
| WT | TG | P value | |
|---|---|---|---|
| Glucose (mmol/liter) | 4.9 ± 1.23 | 8.4 ± 1.86 | 1.38E-4a |
| Insulin (mU/liter) | 4.8 ± 0.19 | 4.9 ± 0.25 | 0.135 |
| FFA (mmol/liter) | 0.4 ± 0.10 | 0.4 ± 0.11 | 0.848 |
| Triglyceride (mg/dl) | 182.8 ± 34.75 | 197.3 ± 43.46 | 0.420 |
| Cholesterol (mg/dl) | 164.9 ± 38.63 | 174.2 ± 49.20 | 0.643 |
| Body weight (g) | 27.2 ± 2.21 | 27.4 ± 2.23 | 0.812 |
| SBP (mm Hg) | 107.1 ± 7.02 | 130.2 ± 7.89 | 1.81E-6a |
All parameters except the last two were measured in the plasma. Data were shown as means ±sd (n = 10). FFA, Free fatty acids; SBP, systolic blood pressure; TG, transgenic WT, wild-type.
a
P < 0.01 vs. WT mice.