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. 2012 Jun 14;26(8):1316–1326. doi: 10.1210/me.2011-1180

Fig. 5.

Fig. 5.

Rimonabant exposure restores CART3 expression in fasted larvae. A–D, Effects of rimonabant exposure conjugated with 4 d fasting on CART expression in 12 dpf larvae monitored by Q-PCR. Note that CART2b (C) and CART3 (D) expression is restored in fasted larvae exposed to rimonabant. The data represent mean ± sem values from six zebrafish larvae. E, Expression of CART3 is restored in cell coexpressing CB1 in fasted 12 dpf larvae exposed to rimonabant. CART3 expression in the hypothalamus (4) and in the medulla oblongata (8, 12) is restored in fasted larvae treated with rimonabant. Expression in the tegmentum remains unaffected (7, 11). Panels 1–4 and 9–12, transverse sections; panels 5–8, lateral views. NS, Not significant; *, P < 0.05; **, P < 0.01.