Figure 6.

Interphase fluorescent in situ hybridization detection of NTRK3 gene rearrangement. Green signals represent 5′NTRK3; and red signals, 3′NTRK3. In comparison to the 5′/3′-fusion signals seen in normal cells, multiple signals for 3′NTRK3 and one separated signal for 5′NTRK3 were observed in samples 930 and 4583; and a single 3′NTRK3 signal pattern (loss of the signal for 5′NTRK3) was observed in sample 3509. Original magnification, ×63.