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. 2017 Apr 5;89(9):4808–4816. doi: 10.1021/acs.analchem.6b03510

Figure 4.

Figure 4

Bioluminescence imaging of substrates with ES-2-Fluc in nude mouse brain: (a) representative bioluminescence images after intraperitoneal injection of dLuc, aLuc, and cybLuc (1 mM, 0.2 mL) over time; (b) total flux for mice with dLuc, aLuc, and cybLuc (1 mM, 0.2 mL) from above; (c) total flux for mice with dLuc, aLuc, and cybLuc at plateau points (dLuc, 10 min; aLuc, 15 min; cybLuc, 35 min). All assays were performed in triplicate and presented as the mean ± SEM.