Table 1.
Genotypes, mice, and nomenclature
| Promoter | Nomenclature | Granular neurons | GABAergic neurons |
Glia |
Ref. | ||
|---|---|---|---|---|---|---|---|
| Purkinje cells | GABAergic inter-neurons | OL | Astrocytes | ||||
| Sycp1 (synaptonemal complex protein 1) | TRαAMI/S | 100 | 100 | 100 | 100 | 100 | 69 |
| Nes (Nestin) | TRαAMI/N | 100 | 100 | 100 | 100 | 100 | 70 |
| Cnp (2′,3′-cyclic nucleotide 3′- phosphodiesterase) | TRαAMI/C | 0 | 74.1 ± 11.4 | 0% | 91.6 ± 7.2 | 0 | 39 |
| Pcp2 (L7, Purkinje cell protein 2) | TRαAMI/liter | 0 | 98.3 ± 4.1 | 0 | 0 | 0 | 71 |
| Ptf1a (pancreas transcription factor 1a) | TRαAMI/P | 0 | 72.5 ± 17.3 | 87.3 ± 7.1 | 0 | 0 | 72 |
| Tamoxifen inducible CreERt2 | |||||||
| Slc1a3 (Glast, solute carrier 1a3) | TRαAMI/S/Gt2/Pna | 0 | 0 | 0 | 0 | 92.8 ± 4.9 | 73 |
| Pdgfra (platelet-derived growth factor receptor, α polypeptide) | TRαAMI/S/Pt2/Pna | >99b | >99b | >99b | 98.7 ± 2.3 | >99b | 40 |
% of YFP+ observed at P15 in TRαAMI/ROSAYFP/CRE cerebellum.
a
Pn, Postnatal day of tamoxifen treatment (P1 for initial characterization); OL, oligodendrocyte lineage, characterized using Olig2 staining. n = 3 for each phenotype.
b
No DAPI+/YFP− cells detected.