Table 2.
Second-line phonotypic and genotypic drug resistance pattern of multidrug-resistant Mycobacterium tuberculosis isolates
| Drug resistance pattern* | Total (no/%) | Type of mutations conferring resistance† | |||
|---|---|---|---|---|---|
| gyrA A90V | gyrA D94N/D94Y | gyrA D94G | rrs A1401G | ||
| M + O | 5 | 3 | 1 | 1 | – |
| M | 4 | 1 | – | 3 | – |
| O | 1 | – | – | 1 | – |
| A + K + C | 2 | – | – | – | 2 |
| K + C | 1 | – | – | – | 1 |
| Total | 13 (15.7) | 4 (4.8%) | 1 (1.2%) | 5 (6%) | 3 (3.6%) |
*
A = amikacin; C = capreomycin; K = kanamycin; M = moxifloxacin; O = ofloxacin. The table shows the corresponding mutations in phenotypic resistant isolates.
†
The mutations detected by the Genotype MTBDRsl version-01 assay.