Table 3.

Genetic and demographical diversity among second-line drug-resistant Mycobacterium tuberculosis isolates

Case	Country of origin	Age/sex	Infection type	Treatment history	Strain lineage*	Mutations in gene codon
						katG	inhA	rpoB	gyrA	rrs
1	Indonesian	35/Female	PTB	New	Beijing	–	C15T	S531L	A90V	–
2	Saudi	31/Male	PTB	PT†	Delhi/CAS	S315T1	–	S531L	A90V	–
3	Pakistan	42/Male	PTB	New	EAI	–	C15T	S531L	A90V	–
4	Saudi	40/Male	PTB	PT	EAI	–	C15T	S531L	A90V	–
5	Saudi	21/Female	PTB	PT	Delhi/CAS	S315T1	–	S531L	D94N/D94Y	–
6	Ethiopian	30/Male	PTB and EPTB	New	Ghana	S315T1	–	S531L	D94G	–
7	Saudi	43/Male	PTB	PT	EAI	S315T1	–	S531L	D94G	–
8	Yemeni	20/Female	PTB	New	Uganda-I	S315T1	–	S531L	D94G	–
9	Saudi	41/Male	PTB	New	Delhi/CAS	S315T1	–	S531L	D94G	–
10	Saudi	72/Female	PTB	New	S	S315T1		S531L	D94G	–
11	Senegal	40/Male	PTB	New	Cameroon	S315T1	–	S531L	–	A1401G
12	Yemeni	23/Male	PTB	PT	Cameroon	–	C15T	S531L	–	A1401G
13	Filipino	43/Male	PTB	New	EAI	–	C15T	S531L	–	A1401G

EAI = East African Indian; EPTB = extrapulmonary tuberculosis; PTB = pulmonary tuberculosis.

^*Defined using www.miru-vntrplus.org database.

^†Previously treated (> 1 month of treatment received).