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. 2017 May 3;96(5):1117–1123. doi: 10.4269/ajtmh.16-0904

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©The American Society of Tropical Medicine and Hygiene

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Figure 2. — Second derivative absorption spectra of different active pharmaceutical ingredient (API) groups matched with the spectra of the associated API standards, when available. (A) Shows artemether-lumefantrine, (B) shows dihydroartemisinin-piperaquine, (C) show artesunate-amodiaquine, and (D) shows artesunate-sulfamethozypyrazine. Artesunate–amodiaquine is a combination therapy in which the two stated active pharmaceutical ingredients are formulated as either a bilayer or as separate tablets. This allowed their spectra to be collected and presented separately. The spectra in (C) represent scans from both bilayer tablet and multi-tablet doses.