Table 1.
Clinical characteristics of malaria-resistant and nonresistant children, the Mother–Offspring Malaria Study, 2002–2006
| Characteristic | Malaria resistant | Nonresistant |
|---|---|---|
| Sample size | 63 | 624 |
| Mean duration of follow-up (range), weeks* | 103.0 (52–184) | 126.6 (52–192) |
| Median (IQR) time (weeks) to first infection | NA | 30 (18–52) |
| Blood smear positive by 6 months | NA | 277 (44.4%) |
| Blood smear positive by 12 months | NA | 471 (75.5%) |
| Blood smear positive by 18 months | NA | 548 (87.8%) |
| Blood smear positive by 24 months | NA | 588 (94.2%) |
| Number (%) of gaps in routine follow-up† | 137 (5.4%) | 1,610 (4.9%) |
| Median time (range) for gap in follow-up, year 1 (weeks) | 4.0 (3–8) | 4.0 (3–22) |
| Median time (range) for gap in follow-up, year 2+ (weeks) | 8.0 (5–12) | 7.0 (5–48) |
| Mean number (95% CI) of BSneg walk-in visits | 5.0 (4.0, 5.9) | 4.7 (4.4, 5.0) |
| Mean number (95% CI) of BSneg visits with fever (≥ 38°C) | 1.4 (1.0, 1.9) | 1.2 (1.1, 1.3) |
| Mean number (95% CI) of BSneg visits with diarrhea | 0.7 (0.5, 0.9) | 0.8 (0.7, 0.9) |
| Number (%) ever used malaria medication at study visit | 3 (4.8%) | 594 (95.2%) |
| Number (%) ever used malaria medication at home | 4 (6.4%) | 125 (20.0%) |
BSneg = blood smear negative; CI = confidence interval; IQR = interquartile range.
*
P < 0.05.
†
When the time between visits was > 2 weeks in the 1st year and > 4 weeks in the following years, then it was counted as a gap in follow-up.