Table 4.
Associations between cord-blood cytokines and malaria-resistant status in early childhood, the Mother–Offspring Malaria Study, 2002–2006
| Characteristic | Unadjusted | Adjusted* |
|---|---|---|
| OR (95% CI) | OR (95% CI) | |
| IL-1β | ||
| Tertile 1 | Ref | Ref |
| Tertile 2 | 2.7 (1.3, 5.8) | 2.5 (1.1, 5.3) |
| Tertile 3 | 2.1 (0.9, 4.5) | 1.9 (0.9, 4.2) |
| IL-6 | ||
| Tertile 1 | Ref | Ref |
| Tertile 2 | 1.3 (0.6, 2.7) | 1.5 (0.7, 3.1) |
| Tertile 3 | 1.7 (0.9, 3.4) | 1.7 (0.9, 3.5) |
| TNF-α | ||
| Tertile 1 | Ref | Ref |
| Tertile 2 | 1.8 (0.9, 3.8) | 1.9 (0.9, 4.0) |
| Tertile 3 | 1.9 (0.9, 4.0) | 1.8 (0.9, 3.8) |
| TNF-RI | ||
| Tertile 1 | Ref | Ref |
| Tertile 2 | 1.7 (0.8, 3.4) | 1.7 (0.8, 3.4) |
| Tertile 3 | 1.7 (0.8, 3.4) | 1.6 (0.8, 3.3) |
CI = confidence interval; IL = interleukin; OR = odds ratio; TNF = tumor necrosis factor.
*
Model adjusted for bednet use (3-level variable, yes-no-missing) and parity (2-level variable, primigravid vs. secondi-multigravid).