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. 2011 Jan 14;25(3):385–393. doi: 10.1210/me.2010-0446

Fig. 3.

Fig. 3.

Inhibition of Aurora-B abolishes both the delocalization of Hp1β and H3Ser10ph induced by T3. A, H3Ser10ph levels in GH4C1 cells incubated with or without T3 and ZM447439. B, Aurora kinase B and H3Ser10ph protein expression in GH4C1 cells transfected with siRNA targeting Aurora kinase B or a control siRNA. C, Nuclear localization of HP1β in HEK293T after ectopic expression of pSG5-TRα together with hemaglutinin (HA)-tagged HP1β. Cells were treated with ZM447439 in absence or presence of T3. D, H3Ser10ph levels in GH4C1 cells incubated in the presence or absence of T3 and DMSO, SB203580 or U0126.