NDP-MSH induces Nur77, Il6, Cox2, Pck1, and Pdk4 gene expressions in mouse adipose tissue. Mice were ip injected with vehicle (saline) or 1 mg/kg of NDP-MSH and inguinal adipose tissue collected after 4 h. qPCR was used to assay the mRNA levels, and results were normalized against 36b4 and expressed as fold changes (n = 7–8). Statistical significance was calculated using the Mann-Whitney U test, where *, P < 0.05 and ***, P < 0.001.