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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Biomaterials. 2017 Mar 1;128:69–83. doi: 10.1016/j.biomaterials.2017.02.041

Fig. 3. Peptide-functionalized nanoparticles.

Fig. 3

A) Schematic of particle functionalization with CD47-derived “self” peptide for suppressing phagocytosis. B) Total fluorescence quantification by in situ tumor imaging demonstrates increased uptake over time of the peptide-functionalized nanoformulation. C) Schematic of liposome-polycation-DNA nanoparticles incorporated with immunological adjuvant and the HER2/neu-derived peptide being taken up across the cell membrane for anticancer vaccination. D) Survival of mice over 80 days after tumor challenge demonstrates prophylactic efficacy of different nanoformulations. A, B adapted with permission from [58]. Copyright American Association for the Advancement of Science, 2013. C, D adapted with permission from [75]. Copyright Elsevier, 2012.