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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Biomaterials. 2017 Mar 1;128:69–83. doi: 10.1016/j.biomaterials.2017.02.041

Fig. 7. Cell membrane-coated nanoparticles.

Fig. 7

A) Schematic of RBC membrane-coated nanoparticle fabrication via an extrusion method. B) Monitoring of fluorescent nanoparticle signal over time demonstrates enhanced circulation for the membrane-coated nanoparticles. C) Schematic of the different applications towards which platelet membrane-coated nanoparticles can be applied, including targeting of damaged vasculature and pathogen binding. D) Platelet membrane-coated nanoparticles do not target intact endothelium (top), but show significant binding when the endothelial layer is removed (bottom). Scale bar = 200 μm. E) Methicillin-resistant Staphylococcus aureus (top) shows significant binding when incubated with platelet membrane-coated nanoparticles (bottom). Scale bar = 1 μm. A,B adapted with permission from [206]. National Academy of Sciences, 2011. C–E adapted with permission from [229]. Nature Publishing Group, 2015.