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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Lancet Haematol. 2016 Sep 14;3(10):e456–e466. doi: 10.1016/S2352-3026(16)30110-7

Figure 3. Acute Leukoencephalopathy and Diffusion Tensor Imaging of White Matter Integrity at Follow-up.

Figure 3

Figure 3 shows the association between acute leukoencephalopathy and white matter integrity at follow-up within the frontostriatal tract, frontal and parietal lobes. The P-values compare the DTI measures (FA, AD and RD) between survivors with and without acute leukoencephalopathy using general linear modeling, adjusted for current age. All models have been adjusted for false discovery rate. Survivors who developed acute leukoencephalopathy had reduced white matter integrity, demonstrated by lower FA and higher AD and RD indices.

Abbreviation: AD, axial diffusivity; FA, fractional anisotropy; RD, radial diffusivity