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. 2017 May 4;13(5):e1006713. doi: 10.1371/journal.pgen.1006713

Fig 1. The principle of a buffered signaling network.

Fig 1

Red arrows represent activation and green blunt arrows represent inhibition. Inhibitory loops within the network provide buffering; when network components are attacked, release of associated inhibitory loops allows other components of the network to compensate for the loss.