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. 2017 May 4;12(5):e0175922. doi: 10.1371/journal.pone.0175922

Table 4. Adverse events.

Outcome Overall
(n = 87)
Poractant alfa
(n = 42)
Bovine lipid extract surfactant
(n = 45)
Odds Ratio (95% CI) Odds Ratio Adjusted for Strata (95% CI) P Value
Adverse events during or after surfactant administration
 Severe airway obstruction; n 5 0 5 0.09 (< 0.01, 1.67) 0.09 (< 0.01, 1.28) 0.07
 Need for cardiopulmonary resuscitation; n 2 0 2 0.21 (< 0.01, 4.55) 0.33 (0.03–3.57) 0.36
 Pulmonary hemorrhage; n 5 2 3 0.75 (0.14–4.10) 0.87 (0.18–4.31) 0.87
Pneumothorax; n 8 3 5 0.65 (0.16–0.56) 0.59 (0.14–2.51) 0.47
Pulmonary interstitial emphysema; n 2 1 1 1.07 (0.10–11.01) 2.74 (0.28–26.74) 0.39