Table 4. Adverse events.
Outcome | Overall (n = 87) |
Poractant alfa (n = 42) |
Bovine lipid extract surfactant (n = 45) |
Odds Ratio (95% CI) | Odds Ratio Adjusted for Strata (95% CI) | P Value |
---|---|---|---|---|---|---|
Adverse events during or after surfactant administration | ||||||
Severe airway obstruction; n | 5 | 0 | 5 | 0.09 (< 0.01, 1.67) | 0.09 (< 0.01, 1.28) | 0.07 |
Need for cardiopulmonary resuscitation; n | 2 | 0 | 2 | 0.21 (< 0.01, 4.55) | 0.33 (0.03–3.57) | 0.36 |
Pulmonary hemorrhage; n | 5 | 2 | 3 | 0.75 (0.14–4.10) | 0.87 (0.18–4.31) | 0.87 |
Pneumothorax; n | 8 | 3 | 5 | 0.65 (0.16–0.56) | 0.59 (0.14–2.51) | 0.47 |
Pulmonary interstitial emphysema; n | 2 | 1 | 1 | 1.07 (0.10–11.01) | 2.74 (0.28–26.74) | 0.39 |