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PCAF acts to reduce the transcriptional activation by ERRα. ERRα plus PGC-1α coactivator or NKX2.5 was transiently transfected in COS-1 cells with either vector alone (gray bars) or PCAF (black bars) with a luciferase reporter construct driven by the Got1 promoter. **, P < 0.01; Student’s t test. C, Control.
