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. 2017 May 4;12(5):e0177032. doi: 10.1371/journal.pone.0177032

Table 2. Mean annual decline FEV1 (SD), with 95% confidence intervals (95%CI) and 5th percentiles (P5).

Women Men
Variables Mean annual drop (SD) 95%CI, Mean annual decline 5th percentile all 5th percentile healthy Mean annual drop (SD) 95%CI, Mean annual decline 5th percentile all 5th percentile healthy
preBD FEV1 (mL/y) -29.3 (39.6) -31.4, -27.1 -88 -100 -40.5 (49.1) -43.8,-37.2 -125 -149
posBD FEV1 (mL/y) -31.4 (34.8) -33.5, -29.3 -81 -91 -41.7 (47.7) -44.9,-38.4 -121 -126
preBD FEV1 (%P/y) -0.14 (1.9) -0.24, -0.04 -2.9 -3.6 -0.30 (1.7) -0.41,-0.18 -3.2 -4.2
posBD FEV1 (%P/y) -0.17 (1.7) -0.27,-0.06 -2.7 -3.1 -0.29 (1.7) -0.40,-0.18 -3.1 -3.7
preBD FEV1 (%B/y) -1.25 (2.39) -1.38,-1.12 -4.12 -4.92 -1.28 (2.0) -1.41,-1.15 -4.31 -4.70
PosBD FEV1 (% B/y) -1.33 (1.61) -1.43, -1.24 -3.79 -3.91 -1.31 (1.6) -1.42, -1.20 -4.07 -4.60

%P = expressed as percentage of predicted according to PLATINO reference values. %B = expressed as percentage of baseline. 95%CI = 95% confidence interval of the mean. PreBD = pre bronchodilator test; posBD = post bronchodilator test; SD = standard deviation of the sample. 5th percentile value of the whole cohort (all, 1261 women and 858 men with preBD testing, 1203 and 822 with postBD testing) or from the respiratory healthy (207 women and 104 men with preBD testing and 195, 97 with postBD testing). See the supplemental material for declines of zFEV1, FEV1/Height3 and LogFEV1