Table 5. Meta-analysis of association between ALDH2 rs671 polymorphism and EH risk in female participants.
| Category | Subgroup | Genetic comparison |
Na | OR (95%CI) | P b | Test of heterogeneity | |
|---|---|---|---|---|---|---|---|
| P, I2(%) | Effect model | ||||||
| Overall | AA vs. GG | 4 | 1.01 (0.81–1.26) | 0.94 | 0.43, 0.00 | F | |
| AG vs. GG | 5 | 1.02 (0.79–1.31) | 0.90 | 0.01, 0.68 | R | ||
| AA/AG vs. GG | 5 | 1.01 (0.78–1.30) | 0.94 | 0.01, 0.70 | R | ||
| AA vs. AG/GG | 4 | 0.99 (0.79–1.23) | 0.91 | 0.61, 0.00 | F | ||
| A vs. G | 5 | 1.00 (0.83–1.21) | 0.99 | 0.02, 0.66 | R | ||
| Country | China | AA vs. GG | 1 | 0.71 (0.45–1.15) | 0.16 | - | F |
| AG vs. GG | 2 | 0.35 (0.04–2.89) | 0.33 | 0.008, 0.86 | R | ||
| AA/AG vs. GG | 2 | 0.35 (0.04–2.77) | 0.32 | 0.009, 0.85 | R | ||
| AA vs. AG/GG | 1 | 0.75 (0.47–1.19) | 0.22 | - | F | ||
| A vs. G | 2 | 0.38 (0.06–2.58) | 0.32 | 0.01, 0.84 | R | ||
| Japan | AA vs. GG | 3 | 1.12 (0.87–1.45) | 0.38 | 0.97, 0.00 | F | |
| AG vs. GG | 3 | 1.10 (0.95–1.28) | 0.20 | 0.35, 0.5 | R | ||
| AA/AG vs. GG | 3 | 1.10 (0.96–1.26) | 0.15 | 0.40, 0.0 | F | ||
| AA vs. AG/GG | 3 | 1.07 (0.84–1.37) | 0.59 | 0.98, 0.0 | F | ||
| A vs. G | 3 | 1.08 (0.97–1.20) | 0.18 | 0.64, 0.0 | F | ||
a Number of studies
b P for OR
Co-dominant model; dominant model; recessive model; allelic contrast model